Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic diagram of the possible mechanism underlying the effects of thiamine uptake on Edwardsiella piscicida pathogenicity. Exogenous thiamine enters bacterial cells through the thiamine transporter and fuels the pentose phosphate pathway for the biosynthesis of c-di-GMP, which regulates the expression of virulence genes and consequently affects the virulence traits, such as motility and adhesion, leading eventually to altered bacterial pathogenicity.
