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. 2022 Apr 12;14(8):1932. doi: 10.3390/cancers14081932

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Genus-level gut microbiota trajectory in pediatric allo-HSCT patients with different duration of febrile neutropenia. Circos (A) and area (B) plots showing the relative abundance over time of the major genera in the GM of patients with less than or equal to (left) vs. more (right) than three days of fever. Only taxa with mean relative abundance > 20% in at least five samples of the total dataset are shown. PRE, before transplant; P2, at the onset of neutropenia (day −2/+2); P5, at the onset of fever (day +4/+5); TAKE, at engraftment; P20, after engraftment (day +20/+30); (C) Boxplots showing the relative abundance distribution of genera significantly differentially represented over time in patients with different duration of fever. Wilcoxon test, * for p < 0.05.