Table 1.
Clinical and transplant characteristics of enrolled patients. Data are shown for the whole cohort and for each of the three pediatric centers. BM: Bone marrow; MAC: Myeloablative conditioning; MMUD: Mismatched unrelated donor; MSD: Matched sibling donor; MUD: Matched unrelated donor; PBSC: Peripheral blood stem cells; RIC: Reduced intensity conditioning.
| Characteristic | Overall (N = 37) |
Bologna (N = 12) |
Verona (N = 12) |
Wroclaw (N = 13) |
|---|---|---|---|---|
| Age at HSCT—year | 8.3 (1.0–18.0) | 8.8 (1.1–18.0) | 9.0 (1.2–17.6) | 7.2 (1.0–13.7) |
| Malignant disease—no. (%) | 22 (59) | 8 (67) | 8 (67) | 6 (46) |
| Donor—no. (%) | ||||
| MUD | 20 (54) | 6 (50) | 7 (58) | 7 (54) |
| MMUD | 7 (19) | 2 (17) | 4 (33) | 1 (8) |
| Haplo | 5 (14) | 3 (25) | 0 (19) | 2 (15) |
| MSD | 5 (14) | 1 (8) | 1 (8) | 3 (23) |
| Graft type—no. (%) | ||||
| BM | 22 (60) | 9 (75) | 8 (67) | 5 (38) |
| PBSC | 15 (40) | 3 (25) | 4 (33) | 8 (62) |
| Intensity of conditioning regimen—no. (%) | ||||
| MAC | 24 (65) | 10 (83) | 7 (58) | 7 (54) |
| RIC | 13 (35) | 2 (17) | 5 (42) | 6 (46) |