Figure 4.

Unadjusted hazard ratio (A) and adjusted hazard ratio (B) of proximity extension assay-based protein biomarkers associated with a composite vascular event in hemodialysis patients. Hazard ratios (HRs) were presented as a per SD increase in NPX value on proteomics. Multivariable Cox regression models were adjusted for age, gender, smoking status, cause of end-stage kidney disease, diabetes, previous myocardial infarction, previous unstable angina, previous cerebrovascular disease, previous treatment for peripheral artery disease, albumin, phosphate, and C-reactive protein, dialysis modality, dialysis treatment time per week, and dialysis vintage.