Table 3.
Various transporters that penetrate the BBB.
Influx Transporters | Efflux Transporters | Receptor Transporters |
---|---|---|
Choline transporter (ChT) | Peptide transport system-6 (PTs-6) | Insulin receptors (IR) |
Sodium-coupled glucose transporters (SGLTs) | Breast cancer resistant protein (BCRP) | Insulin-like growth factor receptor (IGFR) |
Cationic amino acid transporter (CAT1) | P-glycoprotein (P-gp) | Transferrin receptors (TfR) |
1-type large amino-acid transporter (LAT1) Excitatory amino-acid transporters (EAATs) |
Leptin receptor (LepR) | |
Glucose transporter (GLUT1) (GLUT3) | Low-density lipoprotein receptor (LDLR) | |
Monocarboxylate lactate transporter (MCT1) Receptor for glycation end products (RAGE) |
Neonatal Fc receptor (FcRN) | |
Lactoferrin receptor (LR) |