Skip to main content
. 2022 Mar 29;14(4):736. doi: 10.3390/pharmaceutics14040736

Figure 3.

Figure 3

ARC selectively decrease the release of IL-6 by stimulated endothelial cells. HUVEC were stimulated with (A) LPS (1 μg/mL); (B) Pam3CSK4 (1 μg/mL); (C) TNF-α (3 ng/mL) or (D) IL-1β (0.1 ng/mL) and incubated with nanoarchaeosomes (ARC) or liposomes (LIP) at a concentration of 50 μg/mL for 18 h. Concentrations of IL-6 in supernatants were determined by ELISA (one-way ANOVA followed by a Bonferroni multiple comparisons test; * p < 0.05, ** p < 0.01 and **** p < 0.0001 versus basal; # p < 0.05 between labeled groups). Results are the mean ± SEM of four to five independent experiments.