Table 1.
Formulation | Size (nm ± SD) |
PDI | ζ Potential (mV ± SD) |
TL (mg/mL ± SD) |
RhPE (μg/mL ± SD) |
RhPE/TL (μg/mg ± SD) |
---|---|---|---|---|---|---|
ARC | 168.9 ± 11 | 0.19 ± 0.01 | −41.5 ± 4.5 | 7.5 ± 1.3 | - | - |
LIP | 276.7 ± 11 | 0.30 ± 0.08 | −5.4 ± 1.4 | 7.0 ± 1.7 | - | - |
ARC-RhPE | 159.7 ± 7.6 | 0.19 ± 0.02 | −37.0 ± 4.0 | 6.9 ± 0.6 | 3.2 ± 0.6 | 0.48 ± 0.09 |
LIP-RhPE | 251.1 ± 9.1 | 0.29 ± 0.07 | −3.7 ± 0.6 | 6.0 ± 0.3 | 2.8 ± 0.9 | 0.45 ± 0.12 |
Data are expressed as mean ± standard deviation from five independent batches (n = 3 for RhPE labeled nanovesicles). PDI: Polydispersity Index; SD: Standard Deviation; TL: total lipids.