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Main targets involved in the anxiolytic and antidepressant actions of CBD. A summary of previously published data and those supported by the present work. 5-HT1A: serotonin 1A receptor; CB1r: cannabinoid 1 receptor; CB2r: cannabinoid 2 receptor; AEA: anandamide; FAAH: fatty acid amide hydrolase; GPR55: G-protein-coupled receptor 55; PPARγ: Peroxisome proliferator-activated receptor gamma; TRKb/mTOR: Tropomyosin receptor kinase B/mammalian target of rapamycin.
