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. 2022 Apr 14;14(8):1601. doi: 10.3390/polym14081601

Table 1.

Types, classes and location of collagen in tissues. Adapted from [45] with additional data from: [46].

Type Location Class
I tendons, skin, artery walls, cornea, bones Fibrillar
II cartilage, vitreous body Fibrillar
III skin, vessel wall, reticular fibres, intestines, uterus Fibrillar
IV basal membrane, capillaries Network-forming
V skin, placenta, cornea, bones Fibrillar
VI bones, vessels, skin, cornea, cartilage Network-forming
VII skin, mucous membranes, bladder, umbilical cord, amniotic fluid FACIT 1
VIII skin, heart, brain, kidneys, vessels, cartilage, bones Network-forming
IX cornea, vitreous body, cartilage FACIT
X cartilage Network-forming
XI cartilage, intervertebral discs Fibrillar
XII tendons, skin, cartilage FACIT
XIII skeletal muscles, heart, eye, skin, endothelial cells MACIT 2
XIV skin, nerves, tendons, bones, cartilage FACIT
XV skin, capillary vessels, heart, ovaries, testicles, placenta, kidneys MULTIPLEXINs 3
XVI skin, heart, kidneys, smooth muscle FACIT
XVII hemi desmosomes in epitelia MACIT
XVIII liver, kidneys, lungs MULTIPLEXINs
XIX skin, kidneys, liver, placenta, spleen, prostate gland FACIT
XX corneal epithelium FACIT
XXI stomach, skeletal muscles, kidneys, vessels, heart, placenta FACIT
XXII tissue junctions FACIT
XXIII metastatic carcinogenic cells MACIT
XXIV brain, muscle, kidneys, liver, lungs, ovaries, testicles, bones Fibrillar
XXV brain, eye, heart, testicles MACIT
XXVI testicles, ovaries FACIT
XXVII cartilage Fibrillar
XXVIII skin, nerves Network-forming
XXIX skin Network-forming

1 Fibril-associated collagens with interrupted triple helices; 2 Membrane-associated collagens with interrupted triple helices; 3 Multiple triple-helix Network-forming domains and interruptions.