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. 2022 Mar 26;14(4):706. doi: 10.3390/pharmaceutics14040706

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Comparative effectiveness of CBD and CBD inclusion complexes on A172 cells, with respect to time in particular, the concentrations 0.0045 mg/mL (A), 0.009 mg/mL (B), 0.018 mg/mL (C), 0.036 mg/mL (D), 0.071 mg/mL (E), 0.143 mg/mL (F), 0.285 mg/mL (G), and 0.57 mg/mL (H) are presented. The most effective inclusion complexes were the CBD/HP-β-CD and CBD/RM-β-CD in all concentrations between the 24 and 72 h cytotoxicity (p < 0.0001), followed by CBD/DMSO. Each value represents the mean ± SD of triplicate experiments.

Comparative effectiveness of CBD and CBD inclusion complexes on A172 cells, with respect to time in particular, the concentrations 0.0045 mg/mL (A), 0.009 mg/mL (B), 0.018 mg/mL (C), 0.036 mg/mL (D), 0.071 mg/mL (E), 0.143 mg/mL (F), 0.285 mg/mL (G), and 0.57 mg/mL (H) are presented. The most effective inclusion complexes were the CBD/HP-β-CD and CBD/RM-β-CD in all concentrations between the 24 and 72 h cytotoxicity (p < 0.0001), followed by CBD/DMSO. Each value represents the mean ± SD of triplicate experiments.