Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Ron Activation: (1) Classical activation via MSP ligand binding induces dimerization and activation. (2) Ron overexpression facilitates ligand independent activation via homodimerization. (3) Heterodimerization with homolog RTKs including MET. (4) Alternative RON isoforms capable of constitutive activation. (5) Point mutation RON isoforms capable of constitutive phosphorylation.
