Table 1.

Interactions and functions of elastic fibre proteins.

Interaction	Function
Fibrillin-1–fibulin-4 [58,70,71,78]	Tropoelastin cross-linking and deposition onto microfibrils
Fibrillin-1–fibulin-5 [58,70,71,73]
Tropoelastin–fibulin-4 [58,75]
Tropoelastin–fibulin-5 [58,71,72,73,74]
Tropoelastin–fibrillin-1 [80]	Tropoelastin deposition and elastic fibre formation
Fibrillin-1–LTBP4 [79]	Deposition and sequestering of latent TGFβ in the extracellular matrix
Fibulin-4–fibulin-5 [58]	Unknown: Might contribute after initial elastin cross-linking
Tropoelastin–LTBP4 [77]	Unknown: Might contribute to elastic fibre formation
LTBP4–fibulin-5 [50]	Deposition of fibulin-5 and tropoelastin on microfibrils
LTBP4–fibulin-4 [48,63]	Conformational switch of LTBP4 structure, deposition of tropoelastin onto the elongated LTBP4, and deposition of fibulin-4 on microfibrils