Table 4.
Range of minimum inhibitory concentration (MIC) of common antifungal agents described for Fusarium spp. causing onychomycosis (µg/mL).
| Study | Species Complex | Terbinafine | Itraconazole | Fluconazole | Voriconazole | Posaconazole | Efinaconazole | Amphotericin B | 5-Fluorocytosine | Miconazole |
|---|---|---|---|---|---|---|---|---|---|---|
| Hirose et al., 2020 | FOSC | 2 | >16 | 64 | 2 | - | 0.5 | 1 | >64 | 16 |
| Khurana et al., 2018 | FSSC | 4 | 32 | - | 32 | 32 | - | - | - | - |
| Noguchi et al., 2017 | FFSC | >16 | >16 | >64 | 2 | - | 0.13 | 2 | >64 | >16 |
| Gupta et al., 2016 | FFSC | - | >64 | >64 | 4 | 1 | - | 2 | >64 | - |
| Gupta et al., 2016 | FSSC | - | >64 | >64 | 2 | >16 | - | 2 | >64 | - |
| Gupta et al., 2016 | FSSC | - | >64 | >64 | 2 | >16 | - | 2 | >64 | - |
| Gupta et al., 2016 | FSSC | - | >64 | >64 | 2 | 0.5 | - | 2 | >64 | - |
| Gupta et al., 2016 | FFSC | - | >64 | >64 | 4 | 0.5 | - | 0.5 | >64 | - |
| Gupta et al., 2016 | FSSC | - | >64 | >64 | 8 | >16 | - | 2 | >64 | - |
| Gupta et al., 2016 | FFSC | - | >64 | >64 | 1 | 0.5 | - | 2 | >64 | - |
| Gupta et al., 2016 | FSSC | >64 | >64 | 2 | >16 | - | 2 | >64 | - | |
| Gupta et al., 2016 | FSSC | - | >64 | >64 | 2 | >16 | - | 2 | >64 | - |
| Gupta et al., 2016 | FSSC | - | >64 | >64 | 1 | >16 | - | 0.5 | >64 | - |
| Gupta et al., 2016 | FSSC | - | >64 | >16 | 2 | >16 | - | 1 | >64 | - |
| Al-Hatmi et al., 2015 | FSSC | - | > 16 | > 64 | 8 | 0.5 | - | 0.5 | - | - |
| Ikeda et al., 2014 | FSSC | >32 | >8 | >64 | 2 | >16 | - | 4 | >64 | - |
FFSC: Fusarium fujikuroi species complex; FOSC: Fusarium oxysporum species complex; FSSC: Fusarium solani species complex; -: not described.