Table 5.
Three factors, three levels factorial design layout showing factor combinations and response parameters of TLM-FDTs.
| Formulation Number | %Friability (Y1) |
Disintegration Time (s) (Y2) | Rel10 (%) (Y3) |
WT (s) (Y4) |
|---|---|---|---|---|
| F1 | 0.815 ± 0.125 | 21.0 ± 2.60 | 77.1 ± 1.54 | 19 ± 4.20 |
| F2 | 0.974 ± 0.202 | 20.0 ± 2.75 | 61.13 ± 2.36 | 18 ± 3.80 |
| F3 | 0.491 ± 0.233 | 21.0 ± 2.76 | 84.8 ± 1.25 | 18 ± 3.90 |
| F4 | 0.590 ± 0.125 | 25.0 ± 2.56 | 82.92 ± 2.65 | 29 ± 2.80 |
| F5 | 0.938 ± 0.185 | 24.0 ± 3.35 | 91.1 ± 3.44 | 24 ± 3.11 |
| F6 | 0.463 ± 0.224 | 19.0 ± 4.21 | 76.2 ± 1.58 | 22 ± 2.85 |
| F7 | 0.780 ± 0.165 | 18.0 ± 3.54 | 92.5 ± 3.22 | 20 ± 3.44 |
| F8 | 0.688 ± 0.174 | 20.0 ± 3.10 | 75.1 ± 2.95 | 18 ± 4.11 |
| F9 | 0.783 ± 0.266 | 17.0 ± 4.12 | 80.6 ± 2.56 | 16 ± 3.65 |
| F10 | 0.945 ± 0.141 | 19.0 ± 2.18 | 96.1 ± 3.18 | 17 ± 3.11 |
| F11 | 0.560 ± 0.263 | 20.0 ± 3.65 | 74.8 ± 2.19 | 19 ± 2.54 |
| F12 | 0.860 ± 0.101 | 25.0 ± 4.11 | 87.3 ± 1.25 | 27 ± 3.0 |
| F13 | 0.894 ± 0.109 | 22.0 ± 3.25 | 86.0 ± 3.22 | 18 ± 3.48 |
| F14 | 0.229 ± 0.295 | 26.0 ± 2.15 | 91.4 ± 1.25 | 30 ± 4.12 |
| F15 | 0.720 ± 0.212 | 21.0 ± 3.62 | 76.5 ± 3.14 | 19 ± 2.59 |