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. 2022 Mar 30;29(4):2442–2453. doi: 10.3390/curroncol29040198

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Kaplan–Meier curves for survival time according to tumor expression (left) and images showing the protein expression of CDK4 and Cyclin-D1 in patients diagnosed with pancreatic cancer (right A–D). E-Low/Medium = tissue expression classified as low/medium; E-High = tissue expression classified as high; 320× magnification. Histological samples from patients diagnosed with pancreatic cancer were classified as negative expression (0), low/medium (1), and high (3) using the IRS Score method n = 41.