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. 2022 Apr 14;12(4):632. doi: 10.3390/jpm12040632

Figure 1.

Figure 1

Figure 1

CT pulmonary scan and main clinical features of Patient 1 (E193K/F508del), and Patient 2 (R334W/F508del) with cystic fibrosis. The CT scan images show diffuse bronchiectasis in both subjects, with the radiological damage and deterioration rate across the years more marked in Patient 1 despite apparently milder clinical features and a RF mutation combined with F508del (E193K/F508del). Patient 2 (R334W/F508del) has worse lung function spirometry values also influenced by comorbidities and a more evident gastrointestinal involvement.