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. 2022 Apr 12;10(4):881. doi: 10.3390/biomedicines10040881

Figure 6.

Figure 6

pSer129 α-synuclein levels are elevated in the striatum of 12-month-old G2019S KI mice. Western blot analysis of (A) total α-syn and (B) pSer129 α-syn levels in the striatum of 12-month-old G2019S KI and LRRK2 KO mice in comparison with age-matched WT controls. (C) pSer129 α-syn/total α-syn ratio is also shown. Data are expressed as mean ± SEM of n = 8 WT, n = 10 G2019S KI and n = 8 LRRK2 KO mice. Statistical analysis was performed using one-way ANOVA followed by the Tukey test for multiple comparisons. * p < 0.05, different from WT mice.