Table 1.
Baseline demographics and characteristics in the enrolled population.
| aH5N1c a | ||||||
|---|---|---|---|---|---|---|
| Group A (n = 804) |
Group B (n = 799) |
Group C (n = 795) |
All aH5N1c (n = 2398) |
Placebo (n = 798) |
Total (N = 3196) |
|
| Mean age ± SD, years | 58.1 ± 17.67 | 57.5 ± 17.83 | 57.5 ± 18.24 | 57.7 ± 17.91 | 57.7 ± 18.29 | 57.7 ± 18.00 |
| Age group, n (%) | ||||||
| 18 to <65 years | 403 (50.1) | 399 (49.9) | 397 (49.9) | 1199 (50.0) | 398 (49.9) | 1597 (50.0) |
| ≥65 years | 401 (49.9) | 400 (50.1) | 398 (50.1) | 1199 (50.0) | 400 (50.1) | 1599 (50.0) |
| Female, n (%) | 444 (55.2) | 434 (54.3) | 447 (56.2) | 1325 (55.3) | 438 (54.9) | 1763 (55.2) |
| Race, n (%) | ||||||
| White | 668 (83.1) | 679 (85.0) | 674 (84.8) | 2021 (84.3) | 665 (83.3) | 2686 (84.0) |
| Black | 110 (13.7) | 102 (12.8) | 104 (13.1) | 316 (13.2) | 112 (14.0) | 428 (13.4) |
| Asian | 12 (1.5) | 7 (0.9) | 9 (1.1) | 28 (1.2) | 7 (0.9) | 35 (1.1) |
| Native American or Alaskan Native | 6 (0.7) | 4 (0.5) | 5 (0.6) | 15 (0.6) | 3 (0.4) | 18 (0.6) |
| Native Hawaiian or other Pacific Islander | 3 (0.4) | 2 (0.3) | 1 (0.1) | 6 (0.3) | 4 (0.5) | 10 (0.3) |
| Other | 5 (0.6) | 5 (0.6) | 2 (0.3) | 12 (0.5) | 7 (0.9) | 19 (0.6) |
| Hispanic ethnicity, n (%) | 53 (6.6) | 61 (7.6) | 64 (8.1) | 178 (7.4) | 55 (6.9) | 233 (7.3) |
| Mean weight ± SD, kg | 78.86 ± 15.0 | 80.22 ± 15.2 | 78.86 ± 15.3 | 79.31 ± 15.2 | 79.84 ± 15.3 | 79.44 ± 15.2 |
| Mean BMI ± SD, kg/m2 | 27.40 ± 4.2 | 27.86 ± 4.1 | 27.41± 4.2 | 27.56 ± 4.2 | 27.60 ± 4.2 | 27.57 ± 4.2 |
| Previous influenza vaccine in past 12 months, n (%) | ||||||
| All subjects | 430 (53.5) | 416 (52.1) | 426 (53.6) | 1272 (53.0) | 422 (52.9) | 1694 (53.0) |
| Age 18 to <65 years | 145 (36.0) | 137 (34.3) | 139 (35.0) | 421 (35.1) | 123 (30.9) | 544 (34.1) |
| Age ≥65 years | 285 (71.1) | 279 (69.8) | 287 (72.1) | 851 (71.0) | 299 (74.8) | 1150 (71.9) |
Abbreviations: BMI, body mass index; SD, standard deviation. a Group A = Lot 1, No.181053; Group B = Lot 2, No.181054; Group C = Lot 3, No.181675.