Table 1.
Experimental design for various FA-loaded NEs, along with their detected values of response.
| Formula | Independent Variables | Dependent Responses | |||
|---|---|---|---|---|---|
| X1 (g) | X2 (g) | X3 (g) | R1 (nm) | R2 (%) | |
| NE 1 | 2.5 | 0.5 | 1.5 | 191 ± 2.7 | 45.5 ± 2.3 |
| NE 2 | 2.5 | 1 | 1 | 215 ± 3.6 | 42.4 ± 2.4 |
| NE 3 | 2 | 0.5 | 2 | 163 ± 2.6 | 58.0 ± 2.6 |
| NE 4 | 2 | 1 | 1.5 | 159 ± 2.0 | 61.0 ± 3.1 |
| NE 5 | 2 | 1.5 | 1 | 171 ± 3.1 | 53.3 ± 2.7 |
| NE 6 | 1.5 | 0.5 | 1.5 | 144 ± 2.8 | 65.3 ± 3.9 |
| NE 7 | 1.5 | 1 | 1 | 136 ± 2.4 | 68.1 ± 2.8 |
| NE 8 | 1.5 | 1 | 2 | 124 ± 2.2 | 71.3 ± 3.3 |
| NE 9 | 2 | 1 | 1.5 | 155 ± 2.6 | 62.3 ± 3.6 |
| NE 10 | 2.5 | 1 | 2 | 210 ± 3.0 | 43.0 ± 2.9 |
| NE 11 | 2.5 | 1.5 | 1.5 | 226 ± 3.3 | 40.1 ± 2.5 |
| NE 12 | 1.5 | 1.5 | 1.5 | 116 ± 1.9 | 75.6 ± 4.5 |
| NE 13 | 2 | 1.5 | 2 | 152 ± 2.2 | 57.4 ± 2.7 |
| NE 14 | 2 | 0.5 | 1 | 168 ± 2.0 | 55.3 ± 2.9 |
| NE 15 | 2 | 1 | 1.5 | 160 ± 2.5 | 59.4 ± 2.8 |
X1: oil concentration; X2: Tween 80 concentration; X3: Transcutol® P concentration; R1: particle size; R2: in vitro release.