Table 1.

Estimation of the prevalence of recreative opioid use in the six most populated Spanish cities.

	Number of Deaths					Estimation of PROU/1000			Estimation of PROU/1000 without Suicides
Year	Number in Register	Suicides	Ref. Population	% Spanish Population	Deaths/1000	Point	95% LCL	95% UCL	Point	95% LCL	95% UCL
2005	182	15	7,251,688	16.75	0.0251	5.21	3.45	8.62	4.78	3.16	7.91
2006	170	13	7,249,252	16.47	0.0235	4.89	3.24	8.10	4.52	2.99	7.48
2007	136	7	7,233,937	16.15	0.0188	3.92	2.60	6.50	3.72	2.46	6.16
2008	103	8	6,657,856	14.58	0.0155	3.23	2.14	5.35	2.98	1.97	4.93
2009	140	8	7,426,081	16.06	0.0189	3.94	2.61	6.53	3.72	2.46	6.15
2010	143	12	7,436,169	16.00	0.0192	4.04	2.68	6.69	3.71	2.45	6.13
2011	148	18	7,410,976	15.88	0.0200	4.22	2.79	6.99	3.71	2.45	6.14
2012	152	13	7,387,118	15.78	0.0206	4.37	2.89	7.23	4.00	2.64	6.61
2013	141	13	7,344,914	15.72	0.0192	4.09	2.71	6.78	3.72	2.46	6.15
2014	105	22	7,265,367	15.62	0.0145	3.10	2.05	5.13	2.45	1.62	4.06
2015	94	15	7,238,722	15.58	0.0130	2.80	1.85	4.63	2.35	1.55	3.89
2016	105	16	7,263,300	15.64	0.0145	3.11	2.06	5.15	2.64	1.75	4.37
2017	102	14	7,293,097	15.67	0.0140	3.01	1.99	4.98	2.60	1.72	4.30
2018	86	8	7,338,520	15.73	0.0117	2.52	1.67	4.17	2.29	1.51	3.78
2019	105	15	7,407,608	15.75	0.0142	3.04	2.01	5.02	2.60	1.72	4.31