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. 2022 Mar 31;14(4):770. doi: 10.3390/pharmaceutics14040770

Figure 8.

Figure 8

Three-dimensional μ-CT reconstruction images of trabecular bone in ovariectomized mice (OVX), OVX treated with hydroxyapatite-coated superparamagnetic iron oxide nanocomposites (SPIO@15HA) and sham group (A), and trabecular bone mass parameters (B), evidenced after 3 months post-injection. BMD—bone mineral density, BV/TV—bone volume fractions, Tb.N—trabecular number, Tb.Th—trabecular thickness, Tb.Sp—trabecular spacing, Conn.D—connectivity density. Data are expressed as mean ± standard deviation of seven independent mice (n = 7), ns means no significance, and the statistical significance is indicated as * p  <  0.05, ** p  <  0.01, and *** p  <  0.001. See Ref. [370]. Reprinted from an open access source.