Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 14;14(8):1996. doi: 10.3390/cancers14081996

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

¹⁸F-JK-PSMA-7 imaging of mice after targeted alpha therapy with the ²²⁵Ac-TM. Orthogonal sections of PET/CT studies of a representative (A) control and (B) ²²⁵Ac-TM-treated mouse with xenotransplanted PC3-PSCA/PSMA Luc+ tumors are shown. The PET studies were carried out at day 43 after treatment start and 2 h after single intravenous injection of 10 MBq ¹⁸F-JK-PSMA-7 with an imaging duration of 30 min. (C) Kinetics of the ¹⁸F-JK-PSMA-7 in the xenotransplanted untreated PC3-PSCA/PSMA Luc+ tumors (control) expressed as tumor uptake ratio (tumor-to-blood standard uptake ratio, SUR) (mean ± SEM of two animals of the control group) in the periphery (peripheral) and central part (central) of the tumors.