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. 2022 Apr 7;14(4):813. doi: 10.3390/pharmaceutics14040813

Figure 5.

Figure 5

Mbd2 siRNA-loaded liposomes protected mice from BLM-induced pulmonary fibrosis [59]. (A) Schematic diagram of Mbd2 siRNA-loaded liposomes preparation. (B) Representative in vivo images of the mouseintratracheally administrated with DiR-labeled liposomes (Left) and ex vivo images of major organs from mice (Right). (C) Thebiodistribution of liposomes in lungs from BLM-induced mice. (D) Representative results for H&E, Sirius red, and Masson staining indicated intratracheal administration of Mbd2 siRNA–loaded liposomes provided protection for mice against BLM induced pulmonary fibrosis.