Figure 3.

Platelet proteomics of non-pregnant (NP), healthy pregnancy (PC), gestational hypertension (GH), and preeclampsia (PE) patients. (A) Quantification results and multiple group comparison as illustrated by Venn Diagrams. Interquartile boxplot analysis was performed to identify the differently expressed proteins as represented by outliers. (B) Leucine-rich repeat-containing protein 27 (LRRC27) and -42 (LRRC42), and the top changing protein associated with inflammation (GO:0006954): protein S100A9 (S100A9), Cadherin-5 (CDH5), Caspase-12 (CASP12), and apolipoprotein E (APOE). Intensity was quantified by shotgun proteomics. Data are represented as boxplots.