Table 3.
Comparison of the allele frequencies between the NAM population and the continental populations (AFR, AMR, EUR, EAS, and SAS).
| Gene | SNP ID | NAM vs. AFR * | NAM vs. AMR * | NAM vs. EAS * | NAM vs. EUR * | NAM vs. SAS * |
|---|---|---|---|---|---|---|
| ABO | rs55727303 | 1.66 × 10−19 | 1.08 × 10−3 | 1.40 × 10−17 | 6.75 × 10−14 | 8.82 × 10−11 |
| ABO | rs8176748 | 1.58 × 10−19 | 1.00 × 10−8 | 7.06 × 10−16 | 1.52 × 10−20 | 1.29 × 10−20 |
| ABO | rs8176740 | 1.58 × 10−19 | 1.00 × 10−8 | 7.06 × 10−16 | 1.52 × 10−20 | 1.29 × 10−20 |
| ABO | rs8176720 | 3.78 × 10−7 | 2.10 × 10−6 | 4.54 × 10−7 | 3.81 × 10−13 | 9.84 × 10−8 |
| ABO | rs1053878 | 6.04 × 10−7 | 0.149 | 0.001 | 0.020 | 1.000 |
| ABO | rs2073824 | 6.48 × 10−5 | 5.73 × 10−4 | 4.73 × 10−3 | 2.04 × 10−9 | 5.21 × 10−5 |
| ABO | rs559723 | 7.94 × 10−8 | 6.70 × 10−4 | 5.66 × 10−4 | 9.77 × 10−8 | 1.11 × 10−11 |
| ABO | rs616154 | 7.78 × 10−17 | 5.92 × 10−11 | 5.50 × 10−11 | 6.58 × 10−17 | 3.03 × 10−22 |
| ABO | rs2073825 | 1.000 | 3.0 × 10−3 | 0.382 | 0.874 | 0.874 |
| CCR9 | rs147314165 | 4.40 × 10−4 | 4.22 × 10−4 | 8.63 × 10−5 | 8.70 × 10−5 | 9.84 × 10−5 |
| CCR9 | rs7648467 | 2.45 × 10−14 | 0.330 | 0.113 | 0.570 | 0.461 |
| CXCR6 | rs2234355 | 5.37 × 10−15 | 0.398 | 0.035 | 0.100 | 0.037 |
| FYCO1 | rs3733100 | 4.13 × 10−28 | 3.67 × 10−5 | 1.45 × 10−4 | 5.81 × 10−8 | 5.27 × 10−3 |
| FYCO1 | rs3796375 | 2.35 × 10−37 | 4.62 × 10−5 | 6.62 × 10−3 | 1.20 × 10−9 | 3.18 × 10−12 |
| FYCO1 | rs35678722 | 3.39 × 10−3 | 4.22 × 10−4 | 8.63 × 10−5 | 8.70 × 10−5 | 9.84 × 10−5 |
| FYCO1 | rs113517878 | 8.44 × 10−5 | 4.22 × 10−4 | 8.63 × 10−5 | 8.70 × 10−5 | 9.84 × 10−5 |
| FYCO1 | rs4683158 | 0.614 | 0.008 | 1.000 | 2.49 × 10−6 | 0.015 |
| FYCO1 | rs13079478 | 4.40 × 10−4 | 0.578 | 2.76 × 10−4 | 0.410 | 1.51 × 10−6 |
| FYCO1 | rs13059238 | 0.012 | 0.591 | 2.76 × 10−4 | 0.410 | 1.51 × 10−6 |
| FYCO1 | rs33910087 | 0.009 | 0.578 | 0.001 | 0.410 | 1.51 × 10−6 |
| FYCO1 | rs1532071 | 6.14 × 10−25 | 1.36 × 10−6 | 1.32 × 10−5 | 8.95 × 10−10 | 1.82 × 10−3 |
| FYCO1 | rs3733097 | 2.08 × 10−45 | 2.84 × 10−6 | 6.14 × 10−4 | 2.84 × 10−11 | 7.34 × 10−14 |
| FYCO1 | rs751552 | 1.41 × 10−41 | 1.51 × 10−4 | 1.54 × 10−2 | 7.09 × 10−9 | 2.68 x10−11 |
| FYCO1 | rs1873002 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 |
| FYCO1 | rs9875616 | 0.168 | 1.000 | 6.0 x10−3 | 0.045 | 0.685 |
| FYCO1 | rs6800954 | 0.012 | 0.383 | 5.0 × 10−3 | 0.192 | 1.000 |
| FYCO1 | rs41289622 | 4.40 × 10−4 | 0.578 | 2.76 × 10−4 | 0.410 | 1.51 × 10−6 |
| FYCO1 | rs36122610 | 0.011 | 1.000 | 0.012 | 0.093 | 2.44 × 10−8 |
| FYCO1 | rs76597151 | 1.000 | 0.230 | 0.302 | 5.0 × 10−3 | 5.07 × 10−11 |
| FYCO1 | rs17214952 | 1.000 | 0.230 | 0.302 | 5.0 × 10−3 | 1.28 × 10−10 |
| LZTFL1 | rs141398338 | 4.40 × 10−4 | 4.22 × 10−4 | 8.63 × 10−5 | 8.70 × 10−5 | 9.84 × 10−5 |
| LZTFL1 | rs138230559 | 0.712 | 0.288 | 0.213 | 0.213 | 0.218 |
| SLC6A20 | rs140440513 | 2.59 × 10−5 | 4.22 × 10−4 | 8.63 × 10−5 | 8.70 × 10−5 | 9.84 × 10−5 |
| SLC6A20 | rs17279437 | 0.371 | 0.485 | 0.381 | 0.05 | 1.000 |
| SLC6A20 | rs2252547 | 1.08 × 10−14 | 6.54 × 10−12 | 3.18 × 10−6 | 2.12 × 10−11 | 1.95 × 10−8 |
| SLC6A20 | rs2251347 | 1.000 | 0.366 | 0.016 | 0.095 | 0.380 |
| SLC6A20 | rs116638840 | 0.306 | 0.236 | 0.035 | 0.035 | 0.068 |
| SLC6A20 | rs2191027 | 1.000 | 7.90 × 10−5 | 1.000 | 3.58 × 10−8 | 1.0 × 10−3 |
NAM: Amazonian Native American populations; AFR: African populations; AMR: American populations; EAS: East Asian populations; EUR: European populations; SAS: South Asian populations; * p-value defined by Fisher’s exact test. Bold characters indicate a significant difference (p-value < 0.05).