Figure 2.

Analyses of the CSF PTAU levels and mtDNA variants. On the top left, we show the CSF PTAU levels at baseline for the ADNI cohort. On the top right, we show the epistasis network with statistical significance between mtDNA variants and PTAU CSF levels. The network was made from linear model analysis (p-value ≤ 1.0 $\times {10}^{-9}$). Wilcoxon test results and distribution of mtDNA genotype pairs in relation to PTAU levels.