Table 2.
IC50 (μM) of carvacrol in cell-based assay.
| FaDu | K562 | A549 | |
|---|---|---|---|
| SRB | 42.01 ± 11.4 | 81.32 ± 11.83 | – |
| MTT | 9.61 ± 0.05 | – | – |
| NRU | – | – | 80.86 ± 8.28 |
| DHFR | – | – | – |
| ODC | 10.15 ± 0.04 | 12.66 ± 0.23 | – |
| COX-2 | 21.86 ± 5.67 | 39.95 ± 10.24 | – |
| LOX-5 | 82.56 ± 3.14 | – | – |
| HYAL | 88.11 ± 10.38 | 62.01 ± 8.4 | – |
| CATD | – | – | – |
SRB, Sulphorhodamine B; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NRU, Neutral Red Uptake; DHFR, Dihydrofolate reductase; ODC, Ornithine decarboxylase; COX-2, Cyclooxygenase 2; LOX-5, Lipoxygenase 5; HYAL, Hyaluronidase; CATD, Cathepsin D; FaDU, Human squamous cell carcinoma epithelial cell line of hypopharynx; K562, Human myelogenous leukemia cell line; A549, Human adenocarcinoma alveolar basal epithelial cells.