Plg-RKT in human breast cancer progression. Anti-Plg-RKT mAB immunoscores for tissues presented in the CDP breast cancer progression TMA. (A) By anatomical stage: normal breast from nonbreast cancer (n = 23), normal adjacent breast from breast cancer patient (n = 12), DCIS (n = 22), invasive tumor without lymph node involvement (n = 48), invasive tumor with lymph node involvement (n = 50) and invasive tumor with distant metastasis (n = 45). (B) By hormone receptor status: ER and/or PR-positive (n = 95), ER and PR-negative (n = 43). Values are means and SEM, significance by ANOVA with Tukey’s multiple comparison test.