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. 2022 Apr 14;23(8):4280. doi: 10.3390/ijms23084280

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Bliss synergy plots representing the synergistic effects of (A) doxorubicin plus fluoxetine, (B) paclitaxel plus fluoxetine and (C) paclitaxel plus fluphenazine. Adapted from [82,83]. Synergy scores above 10 are considered synergic interactions.