Table 3.
Evaluation of physical stability of selected niosomal formulations and in situ thermosensitive gel thereof after storage at 4 °C for one month.
| Formulation Code | Size (nm) ± SD | PDI ± SD | Tsol–gel
(°C) ± SD |
EE (%) ± SD | ||
|---|---|---|---|---|---|---|
| Curc | GS | |||||
| Niosomes in suspension (Formulation S8) |
Freshly prepared | 401.4 ± 4.3 | 0.36 ± 0.03 | - | 80 ± 1.1 | 36 ± 1.2 |
| After storage | 431 ± 5.2 | 0.45 ± 0.05 | - | 77.9 ± 1.5 | 30.5 ± 1.4 | |
| Niosomes in gel (Formulation G7) |
Freshly prepared | 465 ± 2.3 | 0.32 ± 0.03 | 33 ± 1.1 | 79.5 ± 1.4 | 36 ± 2.2 |
| After storage | 468 ± 2.2 | 0.38 ± 0.02 | 34 ± 0.9 | 79 ± 1.9 | 35.8 ± 2.1 | |