Table 3.

Linear regression analysis on peak enalaprilat concentration.

	Coefficient	SE	p-Value
Intercept	1.413	0.292	2.10 × 10−6	***
Age	0.013	0.004	0.000756	***
Single dose, ln	0.733	0.064	<2 × 10−16	***
Gender_male	−0.192	0.08	0.016837	*
CES1 rs2244613_AC	−0.181	0.081	0.026514	*
CES1 rs2244613_CC	−0.435	0.153	0.004704	**
wt/CES1A1c	−0.003	0.083	0.97459
CES1A1c/CES1A1c	−0.492	0.262	0.061048	.
Adjusted R-squared: 0.3679, p-value: <2.2 × 10−16

ln—natural logarithm, SE—standard error. For genetic predictors, wild-type homozygotes were the reference. Significance codes (p-value): “***”—<0.001, “**”—<0.01, “*”—<0.05, “.”—<0.1.