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Analogs of XJB-5-131. Upper: Schematic diagram of JP4-039 and alternative analogs. The tripeptide moiety in XJB-5-131 is deleted in the truncated JP4-039, which only retains the dipeptide alkene isostere and nitroxide components. Lower: Structures of 3 hypothetical XJB-5-131analogs with decreasing structural complexity from left to right and increasing similarity to JP4-039.
