Fig. 3.

Change from baseline in AS scores over four incobotulinumtoxinA injection cycles for (a) the plantar flexors, (b) other lower limb clinical patterns, and (c) upper limb clinical patterns; FAS, OC. AS score: 5-point scale from 0 (no increase in muscle tone) to 4 (limb rigid in flexion or extension); a decrease in score indicates improvement. ^***p < 0.001 versus study baseline, one-sample t-test. AS = Ashworth Scale; AS-PF=Ashworth Scale of the plantar flexors; FAS = full analysis set; IC = injection cycle; OC = observed cases; SE = standard error.