Figure 2.

SRPX is a marker for glioblastomas. (A) Immunohistochemistry (IHC) of SRPX on FFPE tissue sections from grade 2 (n = 3), grade 3 (n = 3), grade 4 (n = 3) and recurrent tumors of grade 4 (n = 3) (lower panels show primary and recurrent tumor from the same grade patient). White matter biopsies were used as a negative control. Representative images from each grade are shown. Magnification 400×; (B) CGGA data analysis: normalized SRPX expression in glioma tumor grades in the mRNAseq_693 dataset. Kruskal-Wallis was used to compare SRPX mRNA expression among more than two groups and Dunn’s test was used to adjust for multiple comparisons.