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. 2022 Mar 30;29(4):2454–2460. doi: 10.3390/curroncol29040199

Table 1.

Genetic testing criteria according to the consensus meeting of IGLCL (Blair et al. 2020 [10]).

Family Criteria
1 ≥2 cases of gastric cancer in family, independent of age at least >1 proven diffuse subtype 1
2 ≥1 case of diffuse type gastric cancer any age and ≥1 case of lobular breast cancer diagnosed <70 years of age in different family members 1
3 ≥2 cases of lobular breast cancer in family (both diagnosed <50 years of age) 1
Individual Criteria
1 Individuals with diffuse type gastric cancer aged <50 years.
2 Gastric in situ signet ring cells and/or pagetoid spread of signet ring cells in individuals aged <50 years of age
3 Diffuse type gastric cancer at any age in individuals with a personal or family history (first-degree relative) of cleft lip/cleft palate
4 History of diffuse type gastric cancer and lobular breast cancer, both diagnosed <70 years of age
5 Bilateral lobular breast cancer/lobular carcinoma in situ, both diagnosed <70 years of age
6 Diffuse type gastric cancer at any age in individuals of Maori ethnicity
Table 1: Genetic testing criteria according to the consensus meeting of IGLCL (Blair et al. 2020, [10]). 1 Family members must be first- or second-degree blood relatives (according to Blair et al. 2020 [10]).

1 Family members must be first- or second-degree blood relatives (according to Blair et al. 2020 [10]).