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. 2022 Apr 18;14(8):2044. doi: 10.3390/cancers14082044

Table 2.

Advantages and disadvantages of nanoparticle agents for PTT.

Advantages Disadvantages
Organic dye
  • -

    Simultaneous imaging during PTT

  • -

    Excitation/Emission in NIR range

  • -

    Clearance from body

  • -

    Clinical applications (ICG)
  • -

    Low photostability

  • -

    Lack of hydrophilicity

  • -

    Low bioavailability
Inorganic
Metallic		 nanoparticles
  • -

    Excellent photostability

  • -

    Easy synthesis with various sizes, and shapes

  • -

    Simple surface modification

  • -

    Enhanced tumor targeting

  • -

    Tunable optical property (gold NP)
  • -

    Lack of biodegradability

  • -

    Limited clinical applications

  • -

    Absence of standardization in using nanoparticles