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. 2021 Nov 2;31(8):1293–1307. doi: 10.1093/hmg/ddab317

Figure 4.

Figure 4

D564N mutant phenotypes are not due to reduced IGHMBP2 protein. (A) Western blot of brain extracts from PND12 Ighmbp2+/+ (n = 3), Ighmbp2D564N/D564N mice (n = 3) and Ighmbp2D564N/D564N mice ICV injected with a high dose of ssAAV9-IGHMBP2 (n = 3). Actin was used as a loading control. (B) Western blot of spinal cord extracts from PND12 Ighmbp2+/+ (n = 3), Ighmbp2D564N/D564N mice (n = 3) and Ighmbp2D564N/D564N mice ICV injected with a high dose of ssAAV9-IGHMBP2 (n = 3). Actin was used as a loading control.