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. Author manuscript; available in PMC: 2022 Apr 22.
Published in final edited form as: J Autoimmun. 2021 Jun 12;122:102677. doi: 10.1016/j.jaut.2021.102677

Fig. 4. Temporal responses of IAbs from birth to clinical T1D in 10 DAISY subjects.

Fig. 4

A. Time courses of longitudinal IAb levels with a normalized positivity cutoff set to 1.0 (grey dash lines) for all IAbs. B. Cumulative IAb positivity from birth to clinical T1D. All subjects (n=10) were monitored for IAb at 9 months of age, then approximately in 3-month intervals until the age of 2, and then 6-month intervals afterward. Note, IAA, GADA and IA-2A were measured by both RBA and ECL assays, and the earliest age points of positive conversions from one of the two assays were selected for this plot. C. Median first seroconversion year for each IAb in 10 DAISY subjects. The P values are exact solutions of the two-sided Wilcoxon-Mann-Whitney test for paired data sets (n=10).