Table 2.
Performance of HuCaT, BLAST-ref and Norovirus Typing Tool compared to classification based on phylogenetic clustering as gold standard [6]. Query sequences included 1299 norovirus capsid sequences (query 1-Q1), 1299 norovirus polymerase sequences (query 2-Q2) and 239 sapovirus full capsid sequences (query 3-Q3). FASTA files are available upon request.
query | Average Accuracy/concordance (%) | |||||
---|---|---|---|---|---|---|
HuCaT | BLAST-ref | Norovirus Typing Tool | ||||
genogroup | genotype | genogroup | genotype | genogroup | genotype | |
Q1: norovirus capsid | 100 | 100 | 100 | 100 | 100 | 99.9 |
Q2: norovirus polymerase | 100 | 99.9 | 100 | 100 | NA | 99.0 |
Q3: sapovirus capsid | 100 | 100 | 100 | 100 | 100 | 691 |
Current version of the Norovirus Typing Tool does not type sapovirus GIV and GV at the genotype level.