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. 2022 Mar 25;12(4):527. doi: 10.3390/jpm12040527

Figure 2.

Figure 2

Total ghrelin and ghrelin (AG)-to-des-acyl ghrelin (DAG) ratio in plasma before and after drug treatment in male and female pediatric patients. In (A), no changes were reported for total ghrelin plasma levels after 2 months (T1; male, n = 18 and female, n = 18) or 12 months (T2; male, n = 13 and female, n = 13) from the onset of therapy (T0; male, n = 21 and female, n = 22). In (B), no differences were determined between male and female pediatric patients at the same time intervals. Similarly, no changes were observed for the ghrelin-to-DAG ratio based on time (C) and gender (D).