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. 2022 Apr 16;10(4):919. doi: 10.3390/biomedicines10040919

Figure 1.

Figure 1

miRNA expression profile of colonic epithelial cells from Winnie and wild-type mice. (A) Hierarchical clustering using the 18 differentially expressed miRNAs (FDR < 0.05 and fold change threshold >2) discriminating colonic epithelial cells from Winnie mice compared to wild-type mice. Two principal clusters were identified on the basis of differential miRNA expression. (B) PCA based on the expression of differentially expressed miRNA in all samples. PCA showed evident clustering and confirmed the separation of Winnie and wild-type mice.