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. 2022 Apr 11;27(8):2468. doi: 10.3390/molecules27082468

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The effect of synthesized curcumin analogs for the evaluation of memory (1a–1f) in NORT (A) Time spent in the sample phase, (B) Time spent in the test phase, (C) Discrimination index (%) were measured in treated groups (7.5 mg/kg) versus scopolamine (1 mg/kg) treated group. (D) Time spent in the sample phase, (E) Time spent in the test phase, (F) Discrimination index (%) were measured in treated groups (15 mg/kg) versus scopolamine (1 mg/kg) treated group for measuring short-term memory in NORT behavioral mice model; (G) Time spent in the sample phase, (H) Time spent in the test phase, (I) Discrimination index (%) were measured in treated groups (7.5 mg/kg) versus scopolamine (1 mg/kg) treated group. (J) Time spent in the sample phase, (K) Time spent in the test phase, (L) Discrimination index (%) were measured in treated groups (15 mg/kg) versus scopolamine (1 mg/kg) treated group for measuring long-term memory in NORT behavioral mice model. Results were presented in (mean ± SEM), n = 6. ### p < 0.001 vs. normal control. Significantly different values were compared with amnesic group; ***, **, * and ‘ns’ represents p-value < 0.001, <0.01, <0.05, >0.05 respectively.

The effect of synthesized curcumin analogs for the evaluation of memory (1a–1f) in NORT (A) Time spent in the sample phase, (B) Time spent in the test phase, (C) Discrimination index (%) were measured in treated groups (7.5 mg/kg) versus scopolamine (1 mg/kg) treated group. (D) Time spent in the sample phase, (E) Time spent in the test phase, (F) Discrimination index (%) were measured in treated groups (15 mg/kg) versus scopolamine (1 mg/kg) treated group for measuring short-term memory in NORT behavioral mice model; (G) Time spent in the sample phase, (H) Time spent in the test phase, (I) Discrimination index (%) were measured in treated groups (7.5 mg/kg) versus scopolamine (1 mg/kg) treated group. (J) Time spent in the sample phase, (K) Time spent in the test phase, (L) Discrimination index (%) were measured in treated groups (15 mg/kg) versus scopolamine (1 mg/kg) treated group for measuring long-term memory in NORT behavioral mice model. Results were presented in (mean ± SEM), n = 6. ### p < 0.001 vs. normal control. Significantly different values were compared with amnesic group; ***, **, * and ‘ns’ represents p-value < 0.001, <0.01, <0.05, >0.05 respectively.