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. 2022 Apr 11;27(8):2468. doi: 10.3390/molecules27082468

Table 1.

In vitro cholinesterase inhibition potential of compounds (1a1f).

Compound AChEI (IC50 (nM)) BuChEI (IC50 (nM))
1a 2615.42 5347.16
1b 733.84 2159.08
1c 467.18 1356.14
1d 112.52 378.43
1e 3267.95 6635.82
1f 5839.96 9664.71
Donepezil 9.31 33.65

Donepezil was used as positive control. Data were expressed in mean ± SEM, (n = 3), and significantly different values were compared to positive control.