Table 11.
Estimated ORs (95% CI) for PCB congener levels in participants with the combined risk factors for PAH compared to control by LOD ≥ 50%.
| Analyte 1 | Controls (n) |
Subjects with Combined Risk Factors for PAH (n) |
Unadjusted OR (95% CI) |
Adjusted OR 2
(95% CI) |
Adjusted OR 3
(95% CI) |
Adjusted OR 4
(95% CI) |
|---|---|---|---|---|---|---|
| PCB74 | ||||||
| ≥50% | 1406 | 223 | 3.38 (3.37–3.40) | 4.00 (3.98–4.01) | 1.95 (1.94–1.96) | 2.31 (2.30–2.32) a |
| PCB99 | ||||||
| ≥50% | 1845 | 200 | 2.32 (2.31–2.32) | 2.38 (2.37–2.39) | 1.44 (1.43–1.44) | 1.50 (1.49–1.50) a |
| PCB118 | ||||||
| ≥50% | 1411 | 211 | 2.54 (2.53–2.55) | 2.83 (2.82–2.84) | 1.51 (1.50–1.51) | 1.67 (1.66–1.68) a |
| PCB138 | ||||||
| ≥50% | 1837 | 214 | 2.19 (2.18–2.20) | 2.22 (2.22–2.23) | 1.27 (1.27–1.28) | 1.28 (1.27–1.28) a |
| PCB153 | ||||||
| ≥50% | 1835 | 219 | 2.20 (2.19–2.21) | 2.18 (2.17–2.19) | 1.38 (1.380–1.389) | 1.37 (1.36–1.37) a |
| PCB180 | ||||||
| ≥50% | 1832 | 218 | 1.98 (1.97–1.99) | 1.95 (1.95–1.96) | 1.37 (1.37–1.38) | 1.30 (1.29–1.30) a |
1 Lipid adjusted and log-transformed polychlorinated biphenyls (ng/g); 2 Adjusted for gender; 3 Adjusted for age, race, and BMI. 4 Adjusted for age, race, BMI, gender; a p < 0.05.