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. 2022 Apr 8;14(8):1878. doi: 10.3390/cancers14081878

Figure 4.

Figure 4

Gene set enrichment analysis (GSEA) showing EOC tumours with high ABCA1 are enriched for expression of gene sets associated with cholesterol metabolism. (A) GSEA showing enrichment in the Hallmark gene set involved in cholesterol homeostasis. p = 0.008 and false discovery rate (FDR) = 0.021. (B) GSEA showing enrichment in the Gene Ontology (GO) gene set involved in positive regulation of sterol transport. p < 0.001 and FDR = 0.069. n = 498.