Table 1.
Classification of AGEs with respect to different criteria.
| Source | Precursor | Chemical Structure and Ability to Emit Fluorescence | Molecular Weight | Physiological Importance |
|---|---|---|---|---|
| -Endogenous | -Glucose-derived (Glu-AGEs) | -Fluorescent and crosslinked | -Low (LMW AGEs) | -Non-toxic |
| -Exogenous (dietary, dAGEs) | -Fructose-derived (Fru-AGEs) | -Fluorescent and non-crosslinked | -Toxic (TAGEs) | |
| -Glycolaldehyde-derived (Glycol-AGEs) | -Non-fluorescent and crosslinked | -High (HMW AGEs) | ||
| -Glyceraldehyde-derived (Glycer-AGEs) | -Non-fluorescent and non-crosslinked | |||
| -Methylglyoxal-derived (MGO-AGEs) | ||||
| -Glyoxal-derived (GO-AGEs) | ||||
| -3-Deoxyglucosone-derived (3-DG-AGEs) |