Table 2.
Effects of G and GO on coagulation and biochemical parameters (30 days).
| Parameters | Control (Group 1) |
15 Days with G (Group 2) |
30 Days with G (Group 2) |
30 Days with GO (Group 3) |
|---|---|---|---|---|
| Leukocytes (103/mm3) | 4.668 ± 1.22 | 6.75 ± 2.18 | 5.72 ± 0.81 | 3.64 ± 1.43 |
| Basophils (%) | 0.30 ± 0.08 | 0.42 ± 0.13 | 0.14 ± 0.09 | 0.07 ± 0.067 |
| Basophils (103/mm3) | 0.02 ± 0.006 | 0.03 ± 0.017 | 0.01 ± 0.015 | 0.004 ± 0.005 |
| Platelets (103/µL) | 660.50 ± 213.48 | 861.20 ± 305.63 | 464.00 ± 271.70 | 668.20 ± 281.62 |
| Protrombin time (s) | 9.725 ± 0.33 | 9.88 ± 0.31 | 18.08 ± 2.22 * | 19.62 ± 6.39 * |
| Tromboplastin time (s) | 34.975 ± 4.55 | 32.68 ± 5.14 | 131.75 ± 34.27 *** | 85.53 ± 35.38 ** |
| Fibrinogen (mg/dL) | 201.90 ± 6.20 | 191.10 ± 13.15 | 175.78 ± 113.85 | 120.01 ± 52.49 |
| Creatinine (mg/dL) | 0.30 ± 0.04 | 0.36 ± 0.09 | 1.04 ± 0.26 | 0.28 ± 0.06 |
| Total Proteins (g/dL) | 6.40 ± 0.53 | 6.60 ± 0.10 | 6.48 ± 0.44 | 6.26 ± 1.46 |
| AST (U/L) | 89.75 ± 18.25 | 91.20 ± 8.76 | 99.20 ± 31.12 | 118.11 ± 122.41 |
| ALT (U/L) | 30.30 ± 2.99 | 34.60 ± 4.22 | 35.80 ± 6.14 ** | 18.45 ± 5.42 |
| LDH (U/L) | 402.00 ± 98.11 | 537.80 ± 77.93 | 3883.50 ± 1471.50 *** | 777.67 ± 552.59 ** |
| Total Cholesterol (mg/dL) | 90.50 ± 16.22 | 97.00 ± 4.00 | 94.00 ± 28.01 | 84.82 ± 18.94 |
| Triglycerides (mg/dL) | 186.00 ± 68.59 | 271.60 ± 28.08 | 179.00 ± 85.42 | 134.58 ± 65.18 * |
| Beta globulins (%) | 18.40 ± 2.24 | 20.28 ± 0.67 | 22.68 ± 8.24 | 15.03 ± 3.50 |
| Albumin (%) | 50.10 ± 1.84 | 30.29 ± 0.16 | 41.88 ± 12.93 | 55.41 ± 1.23 * |
| Gamma Globulin (%) | 0.975 ± 0.013 | 0.86 ± 0.23 | 0.55 ± 0.25 | 1.58 ± 0.36 ** |
Notes: Each value represents the mean ± SD. * p ≤ 0.05, ** p ≤ 0.01, and *** p ≤ 0.001 when compared with control. Abbreviations: AST: aspartate aminotransferase; ALT: alanine aminotransferase; LDH: Lactate dehydrogenase.