Table 1.
Clinical characteristics of non-responders to three doses of SARS-CoV-2 mRNA vaccination.
| N | Sex | Age | Vaccine | ESKD Cause | Dialysis Vintage (Months) |
Immunosuppressive Treatment | Comorbidities | Previous Humoral Response |
|---|---|---|---|---|---|---|---|---|
| 1 | Male | 88 | BNT162b2 | CNI toxicity | 58 | Tacrolimus | Liver Transplant | No response after two doses |
| 2 | Male | 65 | BNT162b2 | DKD | 40 | No | POEMS syndrome Obesity, Diabetes |
No response after two doses |
| 3 | Female | 82 | BNT162b2 | Unknown | 32 | Cyclophosphamide | Multiple myeloma | Response lost 3 months after the two doses |
| 4 | Male | 54 | mRNA-1273 | Unknown | 114 | Tacrolimus and Mycophenolic acid | Liver transplant Colon cancer HIV, HBV |
No response after two doses |
ESKD: end-stage kidney disease; CNI: calcineurin inhibitors; DKD: Diabetic kidney disease; POEMS: polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, skin changes; HIV: human immunodeficiency virus; HBV: hepatitis B virus.