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. Author manuscript; available in PMC: 2022 Apr 22.
Published in final edited form as: Exp Cell Res. 2020 Oct 29;397(1):112348. doi: 10.1016/j.yexcr.2020.112348

Figure 5.

Figure 5.

Loss of Bmal1 exacerbates muscle damage in TA of dystrophic mice. (A) Representative H/E images of TA cross section of 8, 12 and 20-weeks-old mdx and BmKO/mdx mice (10X). Scale bar: 100 μm. (B) Quantification of the percent of central nuclei-containing myofibers in TA cross section in mdx and BmKO/mdx mice at indicated ages (n=3-5/group). (C-E) TA muscle cross-section area distribution as percentage of total myofibers in 8 (C), 12 (D) and 20 weeks-old (E) mdx and BmKO/mdx mice (n=5-6/group). *, ** P≤0.05 or 0.01 BmKO/mdx vs. mdx control.