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. 2022 Mar 27;9(4):468. doi: 10.3390/children9040468

Table 1.

Demographic, clinical, laboratory, and imaging characteristics and treatment in 35 patients with MIS-C.

Variables Value
Males + 18 (51%)
Age in years * 7 (4–10)
Underlying medical conditions (excluding obesity) + 1 (3%) **
Obesity + 7 (20%)
Duration of symptoms before hospital admission in days * 3 (3–5)
Clinical presentation:
  • -

    Fever +

35 (100%)
  • -

    Conjunctivitis

24 (69%)
  • -

    Rash

17 (49%)
  • -

    Cheilitis

12 (34%)
  • -

    Oral changes

17 (49%)
  • -

    Cervical lymphadenopathy

3 (9%)
  • -

    Abdominal pain

21 (60%)
  • -

    Diarrhea

17 (49%)
  • -

    Meningism

5 (14%)
Length of hospitalization in days * 12 (8–15)
Laboratory values: *
  • -

    WBC count/µL (×1000)

11.7 (7.9–15.7)
  • -

    Lymphocyte count/µL (×1000)

1.2 (1.0–2.1)
  • -

    Platelet count/µL (×1000)

206 (162–252)
  • -

    CRP (mg/L) (ref: <0.5)

145 (106–211)
  • -

    PCT (ng/mL) (ref: <0.05)

2.4 (0.7–11.2)
  • -

    Ferritin (times upper the normal value)

8.3 (5.1–17.2)
  • -

    Fibrinogen (mg/dL) (ref: 180–400)

567 (414–748)
  • -

    D-dimer (ng/mL) (ref: <270)

1084 (806–1844)
  • -

    AST (IU/L) (ref: <58)

35 (21–58)
  • -

    ALT (IU/L) (ref: <40)

28 (16–54)
  • -

    Amylase (U/L) (ref: <80)

35 (25–51)
  • -

    Albumin (g/dL)

3.4 (3.3–3.7)
  • -

    Lowest albumin (g/dL)

2.8 (2.1–3.7)
  • -

    LDH (U/L) (ref: <550)

460 (361–567)
  • -

    Troponin (ng/L) (ref: <14)

21 (8–51)
  • -

    BNP (pg/mL) (ref: <100)

125 (58–745)
  • -

    IL2r (IU) (ref: <710)

4031 (2197–8772)
  • -

    IL6 (pg/mL) (ref: <5)

45 (11–159)
Abnormal findings in imaging: +
  • -

    Abdominal ultrasonography

28 (80%)
  • -

    Electrocardiograms

31 (89%)
  • -

    Echocardiography

26 (74%)
Number of organs/systems involved: +
  • -

    2

1 (3%)
  • -

    3

6 (17%)
  • -

    ≥4

28 (80%)
Medications for MIS-C: +
  • -

    Antimicrobials

32 (91%)
  • -

    IVIG

31 (89%)
  • -

    Bolus of intravenous steroids

17 (49%)
  • -

    Low dose of intravenous steroids (without bolus)

29 (83%)
  • -

    Anakinra

5 (14%)
  • -

    Vasoactive drugs

1 (3%)
  • -

    Enoxaparin

10 (29%)
  • -

    Aspirin

21 (60%)

WBC, white blood cells; AST, aspartate aminotransferase; ALT, alanine aminotransferase; LDH, lactate dehydrogenase; CRP, C-reactive protein; PCT, procalcitonin; BNP, b-type natriuretic peptide; Il2r, interleukin-2 receptor; IL6, interleukin-6; IVIG: intravenous immunoglobulins.; + number (%); * median (interquartile range); ** Pulmonary artery stenosis.